Gt(ROSA)26Sor^{tm1(CAG-RABVgp4,-TVA)Arenk}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-RABVgp4,-TVA)Arenk}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Benjamin Arenkiel
• MGI ID: MGI:5550559
• Synonyms: RPhiGT
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(CAG-RABVgp4,-TVA)Arenk} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:206510
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: The targeting vector contains a loxP-flanked STOP cassette, recombinant rabies glycoprotein G, IRES sequence and TVA (avian leukosis and sarcoma virus subgroup A receptor, chicken) under the control of CAG (CMV enhancer/chicken beta-actin promoter). Expression of the rabies glycoprotein is blocked by the loxP-flanked STOP fragment. (J:206510)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:206510 Takatoh J, et al., New modules are added to vibrissal premotor circuitry with the emergence of exploratory whisking. Neuron. 2013 Jan 23;77(2):346-60
• All: 20 reference(s)