Kalrn^tm2Npl
Targeted Allele Detail

Summary

• Symbol: Kalrn^tm2Npl
• Name: kalirin, RhoGEF kinase; targeted mutation 2, Neuropeptide Laboratory
• MGI ID: MGI:5551304
• Synonyms: KalSR^CKO
• Gene: Kalrn Location: Chr16:33789443-34393647 bp, - strand Genetic Position: Chr16, 24.27 cM
• Alliance: Kalrn^tm2Npl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:206512
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: Exon 13, an exon in the spectrin repeat region (KalSR), was floxed. Flp-mediated recombination removed the neomycin resistance cassette. (J:206512)

Generation of the Kalrn^tm2Npl allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Kalrn Mutation: 171 strains or lines available

References

• Original: J:206512 Mandela P, et al., Kalrn plays key roles within and outside of the nervous system. BMC Neurosci. 2012;13:136
• All: 6 reference(s)