Tg(Jdp2-cre)#Kkyo
Transgene Detail

Summary

• Symbol: Tg(Jdp2-cre)#Kkyo
• Name: transgene insertion, Kazunari K Yokoyama
• MGI ID: MGI:5551455
• Synonyms: Jdp2-Cre
• Transgene: Tg(Jdp2-cre)#Kkyo Location: unknown
• Alliance: Tg(Jdp2-cre)#Kkyo page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Jdp2-cre)#Kkyo expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Jdp2

• Mutation details: A minigene construct was generated with a 2.5 kb fragment of the 5' promoter region of the Jdp2 gene, cre recombinase with a nuclear localization signal (NLS), an IRES site, and an NLS-lacZ sequence followed by an SV40 polyA signal. The linearized construct was used for microinjection of fertilized FVB/N oocytes. 25 founder lines were produced, and were crossed to lacZ (R26R-lacZ) or GFP (Z/EG) reporter animals to assess cre functionality. Numbers for maintained lines are not available at this time. (J:206564)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Jdp2 (species not specified) Summary of all recombinase alleles driven by Jdp2. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:206564 Chiou SS, et al., Control of Oxidative Stress and Generation of Induced Pluripotent Stem Cell-like Cells by Jun Dimerization Protein 2. Cancers (Basel). 2013;5(3):959-84
• All: 1 reference(s)