Tbx20^tm1.2Rph
Targeted Allele Detail

Summary

• Symbol: Tbx20^tm1.2Rph
• Name: T-box 20; targeted mutation 1.2, Richard P Harvey
• MGI ID: MGI:5551507
• Synonyms: Tbx20^f
• Gene: Tbx20 Location: Chr9:24632108-24685580 bp, - strand Genetic Position: Chr9, 10.25 cM
• Alliance: Tbx20^tm1.2Rph page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to insert a single loxP site 5' of the initiation codon in exon 1 and a loxP-flanked neomycin resistance (neo) cassette followed by a beta-galactosidase (lacZ) sequence downstream of exon 3. Mutant mice were bred to mice carrying Tg(rtetR-tetO-cre)40Mhz. Progeny were selected to retain loxP sites in introns 1 and 3, but an excised neomycin selection cassette. (J:98489, J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tbx20 Mutation: 36 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 2 reference(s)