Tbx18^tm1.1Mwmy
Targeted Allele Detail

Summary

• Symbol: Tbx18^tm1.1Mwmy
• Name: T-box18; targeted mutation 1.1, Mark W Majesky
• MGI ID: MGI:5553116
• Synonyms: Tbx18^tm1mwm
• Gene: Tbx18 Location: Chr9:87584853-87613313 bp, - strand Genetic Position: Chr9, 47.06 cM, cytoband E3.2
• Alliance: Tbx18^tm1.1Mwmy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:203805
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An IRES-nlacZ reporter replaced part of exon 1 and all of exon 2. Cre-mediated recombination removed the floxed neomycin resistance cassette inserted downstream of the reporter construct. (J:203805)

Expression

In Mice Carrying this Mutation:	53 assay results
In Structures Affected by this Mutation:	7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tbx18 Mutation: 36 strains or lines available

References

• Original: J:203805 Wu SP, et al., Tbx18 regulates development of the epicardium and coronary vessels. Dev Biol. 2013 Nov 15;383(2):307-20
• All: 1 reference(s)