Ercc1^tm3Jhjh
Targeted Allele Detail

Summary

• Symbol: Ercc1^tm3Jhjh
• Name: excision repair cross-complementing rodent repair deficiency, complementation group 1; targeted mutation 3, Jan H J Hoeijmakers
• MGI ID: MGI:5553260
• Synonyms: Ercc1^f
• Gene: Ercc1 Location: Chr7:19079016-19090449 bp, + strand Genetic Position: Chr7, 9.6 cM
• Alliance: Ercc1^tm3Jhjh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:206925
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exons 7 through 10 were floxed. (J:203815)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ercc1 Mutation: 28 strains or lines available

References

• Original: J:206925 Verhagen-Oldenampsen JH, et al., Loss of ercc1 results in a time- and dose-dependent reduction of proliferating early hematopoietic progenitors. Anemia. 2012;2012:783068
• All: 3 reference(s)