Pcnx2^em4Frk
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pcnx2^em4Frk
• Name: pecanex homolog 2; endonuclease-mediated mutation 4, Wayne N Frankel
• MGI ID: MGI:5554203
• Synonyms: B-2, FS3, Pcnxl2^FS3, TalB
• Gene: Pcnx2 Location: Chr8:126478247-126625056 bp, - strand Genetic Position: Chr8, 73.65 cM
• Alliance: Pcnx2^em4Frk page

Mutation origin

• Strain of Origin: C3Fe.C3-Gria4^spkw1/Frk

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: TALEN mediated recombination produced an 2 bp deletion near the 3' of exon 29 resulting in a frameshift and premature stop codon. (J:228536)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pcnx2 Mutation: 130 strains or lines available

References

• Original: J:228536 Frankel WN, et al., Unraveling genetic modifiers in the gria4 mouse model of absence epilepsy. PLoS Genet. 2014 Jul;10(7):e1004454
• All: 1 reference(s)