Tshr^hyt-3J
Spontaneous Allele Detail

Summary

• Symbol: Tshr^hyt-3J
• Name: thyroid stimulating hormone receptor; hypothyroid 3 Jackson
• MGI ID: MGI:5554389
• Gene: Tshr Location: Chr12:91367767-91507283 bp, + strand Genetic Position: Chr12, 44.51 cM
• Alliance: Tshr^hyt-3J page

Mutation origin

• Strain of Origin: CXB10/HiAJ-Cacna1a^smrl/GrsrJ

Mutation description

• Allele Type: Spontaneous (Not Specified)
• Mutation: Intragenic deletion
• Mutation details: This spontaneous 233 bp intragenic deletion is predicted to result in a frameshift, which, if translated, would introduce 11 novel amino acids beginning at amino acid 442 prior to a premature stop codon. (J:222308)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tshr Mutation: 7 strains or lines available

References

• Original: J:210510 Harris BS, et al., A spontaneous mutation in thyroid stimulating hormone receptor that allows partial fertility in both females and males. MGI Direct Data Submission. 2014
• All: 2 reference(s)