Tg(Slc6a3-icre)9190Gsc
Transgene Detail

Summary

• Symbol: Tg(Slc6a3-icre)9190Gsc
• Name: transgene insertion 9190, Gunther Schutz
• MGI ID: MGI:5554573
• Synonyms: DATCre
• Transgene: Tg(Slc6a3-icre)9190Gsc Location: unknown
• Alliance: Tg(Slc6a3-icre)9190Gsc page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Slc6a3-icre)9190Gsc expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Slc6a3

• Mutation details: The improved codon cre open reading frame was inserted at the translation initiation site of Slc6a3 to create a transgene that drives expression of cre in the brain. Lines 9075 (2 copies of the transgene), 9190 (3 copies) and 9140 (5 copies) were generated. (J:114551)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Slc6a3 (species not specified) Summary of all recombinase alleles driven by Slc6a3. Comparative matrix view of recombinase activities

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:114551 Parlato R, et al., Survival of DA neurons is independent of CREM upregulation in absence of CREB. Genesis. 2006 Oct;44(10):454-64
• All: 2 reference(s)