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Taok2tm1.2Dkap
Targeted Allele Detail
Summary
Symbol: Taok2tm1.2Dkap
Name: TAO kinase 2; targeted mutation 1.2, David Kapfhamer
MGI ID: MGI:5554942
Synonyms: TaoK2tm1Heb
Gene: Taok2  Location: Chr7:126464850-126483875 bp, - strand  Genetic Position: Chr7, 69.25 cM
Alliance: Taok2tm1.2Dkap page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:206781
Parent Cell Line:  PRX-B6N (ES Cell)
Strain of Origin:  C57BL/6NTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 2. An FRT- and loxP-flanked neomycin resistance cassette was inserted downstream of exon 7. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exons 2 through 7. (J:206781)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Taok2 Mutation:  51 strains or lines available
References
Original:  J:206781 Kapfhamer D, et al., Taok2 controls behavioral response to ethanol in mice. Genes Brain Behav. 2013 Feb;12(1):87-97
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory