Gpr83^tm1.2Lex
Targeted Allele Detail

Summary

• Symbol: Gpr83^tm1.2Lex
• Name: G protein-coupled receptor 83; targeted mutation 1.2, Lexicon Genetics
• MGI ID: MGI:5554947
• Gene: Gpr83 Location: Chr9:14771506-14782085 bp, + strand Genetic Position: Chr9, 4.4 cM, cytoband A2-A3
• Alliance: Gpr83^tm1.2Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:206778
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exons 2 and 3. (J:206778)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr83 Mutation: 26 strains or lines available

References

• Original: J:206778 E Vollmer L, et al., Attenuated stress-evoked anxiety, increased sucrose preference and delayed spatial learning in glucocorticoid-induced receptor-deficient mice. Genes Brain Behav. 2013 Mar;12(2):241-9
• All: 1 reference(s)