Tg(Igh-Mir210)#aKgcs
Transgene Detail

Summary

• Symbol: Tg(Igh-Mir210)#aKgcs
• Name: transgene insertion #a, Kenneth G C Smith
• MGI ID: MGI:5555968
• Synonyms: MiR-210 TG
• Transgene: Tg(Igh-Mir210)#aKgcs Location: unknown
• Alliance: Tg(Igh-Mir210)#aKgcs page

Transgene origin

• Strain of Origin: C57BL/6 x CBA

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Igh-Mir210)#aKgcs expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Mir210 (MGI:2676886)

• Mutation details: The heavy chain promoter, IgH intronic enhancer (Emu) and Igk 3' enhancer drive expression of the microRNA precursor. Three unnamed lines were generated. Line #a represents the highest expressing line. (J:205868)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:205868 Mok Y, et al., MiR-210 is induced by Oct-2, regulates B cells, and inhibits autoantibody production. J Immunol. 2013 Sep 15;191(6):3037-48
• All: 1 reference(s)