Tspan2tm1Hbw
Targeted Allele Detail
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| Symbol: |
Tspan2tm1Hbw |
| Name: |
tetraspanin 2; targeted mutation 1, Hauke B Werner |
| MGI ID: |
MGI:5556057 |
| Gene: |
Tspan2 Location: Chr3:102642086-102679626 bp, + strand Genetic Position: Chr3, 45.25 cM, cytoband F3
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| Alliance: |
Tspan2tm1Hbw page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:201143
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
C57BL/6
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Most of exon 1 including the translation start site was replaced with a neo cassette via homologous recombination. Immunoblot analysis confirmed the absence of TSPAN2 protein in purified myelin from homozygous mice.
(J:201143)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Tspan2 Mutation: |
11 strains or lines available
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| Original: |
J:201143 de Monasterio-Schrader P, et al., Uncoupling of neuroinflammation from axonal degeneration in mice lacking the myelin protein tetraspanin-2. Glia. 2013 Nov;61(11):1832-47 |
| All: |
1 reference(s) |
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Analysis Tools
