Tg(H2-L-IL6)40Csk
Transgene Detail

Summary

• Symbol: Tg(H2-L-IL6)40Csk
• Name: transgene insertion 40, Chugai Pharmaceutical Co Ltd
• MGI ID: MGI:5556099
• Synonyms: H-2L^d-hIL6, Tg(IL6)40Csk
• Transgene: Tg(H2-L-IL6)40Csk Location: unknown
• Alliance: Tg(H2-L-IL6)40Csk page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(H2-L-IL6)40Csk expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  IL6 (3569)

  Il6	(MGI:96559)

• Mutation details: A transgenic construct containing the human IL6 gene under the control of the H-2L^ds promoter. Line 40 was generated. (J:207264)

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:207264 Ueda O, et al., Novel genetically-humanized mouse model established to evaluate efficacy of therapeutic agents to human interleukin-6 receptor. Sci Rep. 2013;3:1196
• All: 1 reference(s)