Tdrd12^tm1Yam
Targeted Allele Detail

Summary

• Symbol: Tdrd12^tm1Yam
• Name: tudor domain containing 12; targeted mutation 1, Shinya Yamanaka
• MGI ID: MGI:5556124
• Gene: Tdrd12 Location: Chr7:35168523-35237170 bp, - strand Genetic Position: Chr7, 21.37 cM, cytoband B1
• Alliance: Tdrd12^tm1Yam page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:202012
• Parent Cell Line: RF8 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Exons 3 and 4 were replaced with a beta-geo cassette by promoter trap selection. (J:202012)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tdrd12 Mutation: 64 strains or lines available

References

• Original: J:202012 Pandey RR, et al., Tudor domain containing 12 (TDRD12) is essential for secondary PIWI interacting RNA biogenesis in mice. Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16492-7
• All: 2 reference(s)