Gt(ROSA)26Sor^{tm1(tetO-Sox9)Msan}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(tetO-Sox9)Msan}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Maike Sander
• MGI ID: MGI:5557984
• Synonyms: Rosa26-tetO-Sox9, Rosa26-tetO-Sox9-mCherry
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(tetO-Sox9)Msan} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:202984
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inducible, Inserted expressed sequence, Reporter)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(tetO-Sox9)Msan} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Sox9 (MGI:98371)

• Mutation details: The pTight tetO promoter driving bidirectional expression of Sox9 and mCherry was inserted into the locus. (J:202984)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:202984 Rockich BE, et al., Sox9 plays multiple roles in the lung epithelium during branching morphogenesis. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):E4456-64
• All: 1 reference(s)