Tg(Gnrh1-Kiss1r)#Aeh
Transgene Detail

Summary

• Symbol: Tg(Gnrh1-Kiss1r)#Aeh
• Name: transgene insertion, Allan E Herbison
• MGI ID: MGI:5558110
• Transgene: Tg(Gnrh1-Kiss1r)#Aeh Location: unknown
• Alliance: Tg(Gnrh1-Kiss1r)#Aeh page

Reduced gonadal size in Kiss1r^tm1.1Aeh/Kiss1r^tm1.1Aeh Tg(Gnrh1-cre)1Dlc mice is rescued by the Tg(Gnrh1-Kiss1r)#Aeh transgene

Show the 1 phenotype image(s) involving this allele.

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Gnrh1-Kiss1r)#Aeh expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Kiss1r (MGI:2148793)

• Mutation details: The transgene contains the cDNA replaced the first exon of Gnrh1 in BAC (RP23-358B23). The promoter drives neuron-specifc expression. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:206044)

Generation of the Tg(Gnrh1-Kiss1r)#Aeh transgene

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:206044 Kirilov M, et al., Dependence of fertility on kisspeptin-Gpr54 signaling at the GnRH neuron. Nat Commun. 2013;4:2492
• All: 6 reference(s)