Tg(Nphs1-rtTA*3G)8Jhm
Transgene Detail
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| Symbol: |
Tg(Nphs1-rtTA*3G)8Jhm |
| Name: |
transgene insertion 8, Jeffrey H Miner |
| MGI ID: |
MGI:5559153 |
| Synonyms: |
NEF-rtTA, NEFTA, Nphs1-rtTA-3G |
| Transgene: |
Tg(Nphs1-rtTA*3G)8Jhm Location: unknown
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| Alliance: |
Tg(Nphs1-rtTA*3G)8Jhm page
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| Strain of Origin: |
(C57BL/6J x CBA/J)F2
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| Transgene Type: |
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Transgenic (Transactivator) |
| Mutation: |
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Insertion
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Mutation details: The 4.1 kb mouse promoter drives podocyte-specific expression of a modified reverse tetracycline transactivator (rtTA*3G). Thirty-six lines were generated. Line 8 has the highest and most specific doxycycline-dependent expression in all podocytes.
(J:207595)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:207595 Lin X, et al., Feasibility of repairing glomerular basement membrane defects in alport syndrome. J Am Soc Nephrol. 2014 Apr;25(4):687-92 |
| All: |
6 reference(s) |
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Analysis Tools
