Tg(tetO-COL4A3/Col4a3)#aJhm
Transgene Detail
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| Symbol: |
Tg(tetO-COL4A3/Col4a3)#aJhm |
| Name: |
transgene insertion #a, Jeffrey H Miner |
| MGI ID: |
MGI:5559154 |
| Synonyms: |
T-Col4a3 |
| Transgene: |
Tg(tetO-COL4A3/Col4a3)#aJhm Location: unknown
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| Alliance: |
Tg(tetO-COL4A3/Col4a3)#aJhm page
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| Strain of Origin: |
(C57BL/6J x CBA/J)F2
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| Transgene Type: |
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Transgenic (Inducible, Inserted expressed sequence) |
| Inducer: |
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doxycycline/tetracycline |
| Mutation: |
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Insertion
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Mutation details: The tetracycline regulatory element (tetO) drives inducible expression of a fusion of the human cDNA fragment encoding the first 133 amino acids and the mouse cDNA fragment encoding the remaining 1536 amino acids. Eight unnamed lines were generated. The pound symbol (#) is used when no line is specified and/or lines are pooled. Line #a represents the best expression line. Other lines exhibited novel expression in the intestine and spleen.
(J:207595)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:207595 Lin X, et al., Feasibility of repairing glomerular basement membrane defects in alport syndrome. J Am Soc Nephrol. 2014 Apr;25(4):687-92 |
| All: |
2 reference(s) |
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Analysis Tools
