Foxi3^tm1.2Akg
Targeted Allele Detail

Summary

• Symbol: Foxi3^tm1.2Akg
• Name: forkhead box I3; targeted mutation 1.2, Andrew K Groves
• MGI ID: MGI:5559167
• Synonyms: Foxi3-del
• Gene: Foxi3 Location: Chr6:70933590-70938050 bp, + strand Genetic Position: Chr6, 32.14 cM
• Alliance: Foxi3^tm1.2Akg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:207523
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting vector was designed to insert a loxP site upstream of exon 2 followed by a frt-flanked neomycin resistance (neo) cassette, and a second loxP site downstream of exon 2. Mutant mice were bred with Tg(CMV-cre)1Cgn mice to remove the floxed region including exon 2. (J:207523)

Expression

In Mice Carrying this Mutation:	33 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	28 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Foxi3 Mutation: 22 strains or lines available

References

• Original: J:207523 Edlund RK, et al., Foxi transcription factors promote pharyngeal arch development by regulating formation of FGF signaling centers. Dev Biol. 2014 Jun 1;390(1):1-13
• All: 6 reference(s)