Pcgf2^tm2.1Hko
Targeted Allele Detail

Summary

• Symbol: Pcgf2^tm2.1Hko
• Name: polycomb group ring finger 2; targeted mutation 2.1, Haruhiko Koseki
• MGI ID: MGI:5559317
• Synonyms: Mel18^GFP
• Gene: Pcgf2 Location: Chr11:97579649-97591323 bp, - strand Genetic Position: Chr11, 61.06 cM, cytoband C1-C3
• Alliance: Pcgf2^tm2.1Hko page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:204987
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: An EGFP gene and floxed neomycin resistance cassette were inserted into the last coding exon to generate a fusion product. Cre-mediated recombination removed the selection cassette. (J:204987)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pcgf2 Mutation: 48 strains or lines available

References

• Original: J:204987 Isono K, et al., SAM domain polymerization links subnuclear clustering of PRC1 to gene silencing. Dev Cell. 2013 Sep 30;26(6):565-77
• All: 1 reference(s)