Ptger2^tm1.1Kand
Targeted Allele Detail

Summary

• Symbol: Ptger2^tm1.1Kand
• Name: prostaglandin E receptor 2 (subtype EP2); targeted mutation 1.1, Katrin I Andreasson
• MGI ID: MGI:5559328
• Synonyms: EP2^lox
• Gene: Ptger2 Location: Chr14:45225652-45241277 bp, + strand Genetic Position: Chr14, 22.68 cM
• Alliance: Ptger2^tm1.1Kand page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:202677
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1 and an FRT flanked neo cassette and loxP site were inserted downstream of exon1. Flp mediated recombination removed the neo cassette. (J:202677)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptger2 Mutation: 31 strains or lines available

References

• Original: J:202677 Johansson JU, et al., Suppression of inflammation with conditional deletion of the prostaglandin E2 EP2 receptor in macrophages and brain microglia. J Neurosci. 2013 Oct 2;33(40):16016-32
• All: 6 reference(s)