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Tg(KRT14-HPV8)61Vuc
Transgene Detail
Summary
Symbol: Tg(KRT14-HPV8)61Vuc
Name: transgene insertion 61, Herbert Pfister
MGI ID: MGI:5559370
Transgene: Tg(KRT14-HPV8)61Vuc  Location: unknown  
Alliance: Tg(KRT14-HPV8)61Vuc page
Transgene
origin
Strain of Origin:  (DBA x C57BL/6)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThis transgene consists of the human keratin 14 promoter, intron 2 of the rabbit beta-globin gene, the complete early region and parts of the noncoding region and the L2-open reading frame of human papillomavirus type 8 (HPV8), and keratin 14 polyadenylation sequence. The keratin 14 promoter drives expression of the transgene in basal cells of the squamous epithelium. Three lines were generated: 9, 61, 85. Line 61 has 50 copies of the transgene. (J:96784)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:96784 Schaper ID, et al., Development of skin tumors in mice transgenic for early genes of human papillomavirus type 8. Cancer Res. 2005 Feb 15;65(4):1394-400
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory