Septin7^tm1Ksh
Targeted Allele Detail

Summary

• Symbol: Septin7^tm1Ksh
• Name: septin 7; targeted mutation 1, Makato Kinoshita
• MGI ID: MGI:5559527
• Synonyms: Sept7^fl
• Gene: Septin7 Location: Chr9:25163735-25219867 bp, + strand Genetic Position: Chr9, 10.25 cM
• Alliance: Septin7^tm1Ksh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:205987
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 3 was floxed. (J:205987)

Expression

In Mice Carrying this Mutation:

70 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Septin7 Mutation: 36 strains or lines available

References

• Original: J:205987 Ageta-Ishihara N, et al., Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation. Nat Commun. 2013;4:2532
• All: 3 reference(s)