Tg(Vil1-Lin28b,-tdTomato)MedAru
Transgene Detail

Summary

• Symbol: Tg(Vil1-Lin28b,-tdTomato)MedAru
• Name: transgene insertion Med, Anil K Rustgi
• MGI ID: MGI:5560201
• Synonyms: Vil-Lin28b^Med
• Transgene: Tg(Vil1-Lin28b,-tdTomato)MedAru Location: unknown
• Alliance: Tg(Vil1-Lin28b,-tdTomato)MedAru page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Vil1-Lin28b,-tdTomato)MedAru expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Lin28b (MGI:3584032)

• Mutation details: A 13 kb mouse villin promoter drives expression of a FLAG-HA-tagged mouse Lin28b cDNA and an IRES-tdTomato expression cassette. This line shows a medium level of expression. (J:202923)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:202923 Madison BB, et al., LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7. Genes Dev. 2013 Oct 15;27(20):2233-45
• All: 3 reference(s)