Mef2a^tm1.1Limm
Targeted Allele Detail

Summary

• Symbol: Mef2a^tm1.1Limm
• Name: myocyte enhancer factor 2A; targeted mutation 1.1, Lisa Monteggia
• MGI ID: MGI:5560553
• Synonyms: Mef2a^loxP
• Gene: Mef2a Location: Chr7:66880911-67022606 bp, - strand Genetic Position: Chr7, 36.72 cM
• Alliance: Mef2a^tm1.1Limm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:207812
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the selection cassette and left exon 2 floxed. (J:207812)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mef2a Mutation: 36 strains or lines available

References

• Original: J:207812 Akhtar MW, et al., In vivo analysis of MEF2 transcription factors in synapse regulation and neuronal survival. PLoS One. 2012;7(4):e34863
• All: 9 reference(s)