Mpst^tm1Nori
Targeted Allele Detail

Summary

• Symbol: Mpst^tm1Nori
• Name: mercaptopyruvate sulfurtransferase; targeted mutation 1, Noriyuki Nagahara
• MGI ID: MGI:5560811
• Gene: Mpst Location: Chr15:78290918-78298213 bp, + strand Genetic Position: Chr15, 37.47 cM, cytoband E2
• Alliance: Mpst^tm1Nori page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:207803
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted into exon 2. (J:207803)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mpst Mutation: 23 strains or lines available

References

• Original: J:207803 Nagahara N, et al., Antioxidant enzyme, 3-mercaptopyruvate sulfurtransferase-knockout mice exhibit increased anxiety-like behaviors: a model for human mercaptolactate-cysteine disulfiduria. Sci Rep. 2013;3:1986
• All: 1 reference(s)