Dp(16Tiam1-Il10rb)8Yey
Targeted Allele Detail

Summary

• Symbol: Dp(16Tiam1-Il10rb)8Yey
• Name: duplication, Chr 16, Y Eugene Yu 8
• MGI ID: MGI:5561088
• Synonyms: Dp(16)3Yey, Dp(16)8Yey, Dp(16Tiam1-Il10rb)3Yey, Ts5Yey
• Gene: Dp(16Tiam1-Il10rb)8Yey Location: unknown Genetic Position: Chr16, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:208104
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted
• Mutations: Duplication, Insertion
• Dp(16Tiam1-Il10rb)8Yey involves 43 genes/genome features (Gm22933, Gm35834, Gm35774 ...) View all
• Mutation details: This duplication was generated by recombination between two MICER clone insertions (MHPn374h24 and MHPP321i13). The 2.1 Mb duplication spans Tiam1 to Il10rb. The duplication retains the puromycin and neomycin resistance cassettes from the original MICER clones. (J:208104)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dp(16Tiam1-Il10rb)8Yey Mutation: 1 strain or line available

References

• Original: J:208104 Liu C, et al., Engineered chromosome-based genetic mapping establishes a 3.7 Mb critical genomic region for Down syndrome-associated heart defects in mice. Hum Genet. 2014 Jun;133(6):743-53
• All: 1 reference(s)