Bcl2l11^tm6.1Boui
Targeted Allele Detail

Summary

• Symbol: Bcl2l11^tm6.1Boui
• Name: BCL2 like 11; targeted mutation 6.1, Philippe Bouillet
• MGI ID: MGI:5562690
• Synonyms: Bim^Conditional, Bim^f, Bim^Flox
• Gene: Bcl2l11 Location: Chr2:127967958-128004467 bp, + strand Genetic Position: Chr2, 62.23 cM, cytoband F3-G1
• Alliance: Bcl2l11^tm6.1Boui page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:208318
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 2, 3 and 4 were floxed. Flp-mediated recombination removed the FRT-flanked hygromycin resistance cassette. (J:208318)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Bcl2l11 Mutation: 36 strains or lines available

References

• Original: J:208318 Raynor J, et al., IL-15 Fosters Age-Driven Regulatory T Cell Accrual in the Face of Declining IL-2 Levels. Front Immunol. 2013;4:161
• All: 11 reference(s)