Scarf1^tm1Tkms
Targeted Allele Detail

Summary

• Symbol: Scarf1^tm1Tkms
• Name: scavenger receptor class F, member 1; targeted mutation 1, Terry K Means
• MGI ID: MGI:5562868
• Gene: Scarf1 Location: Chr11:75404366-75417408 bp, + strand Genetic Position: Chr11, 45.92 cM
• Alliance: Scarf1^tm1Tkms page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:208237
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced exons 1 through 8, which encode the entire extracellular and transmembrane domains. (J:208237)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Scarf1 Mutation: 40 strains or lines available

References

• Original: J:208237 Ramirez-Ortiz ZG, et al., The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity. Nat Immunol. 2013 Sep;14(9):917-26
• All: 1 reference(s)