Rnf7^tm1.1Ysun
Targeted Allele Detail

Summary

• Symbol: Rnf7^tm1.1Ysun
• Name: ring finger protein 7; targeted mutation 1.1, Yi Sun
• MGI ID: MGI:5562909
• Synonyms: Sag^fl, SAG^flox
• Gene: Rnf7 Location: Chr9:96352990-96360728 bp, - strand Genetic Position: Chr9, 50.63 cM, cytoband D2.3
• Alliance: Rnf7^tm1.1Ysun page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:207982
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A FRT-flanked neo cassette was inserted upstream of exon 1 and a loxP site was inserted before the neo cassette and following exon 1. The FRT-flanked neo cassette was removed via FLP-mediated recombination. (J:207982)

Tumor Data

List all tumor models in MMHCdb carrying Rnf7^tm1.1Ysun

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rnf7 Mutation: 17 strains or lines available

References

• Original: J:207982 Li H, et al., Inactivation of SAG/RBX2 E3 ubiquitin ligase suppresses KrasG12D-driven lung tumorigenesis. J Clin Invest. 2014 Feb 3;124(2):835-46
• All: 7 reference(s)