Ash1l^{Tn(pb-Act-RFP)1.AF0-180T25Zhu}
Transposon induced Allele Detail

Summary

• Symbol: Ash1l^{Tn(pb-Act-RFP)1.AF0-180T25Zhu}
• Name: ASH1 like histone lysine methyltransferase; transposon insertion 1.AF0-180T25, Yuan Zhuang
• MGI ID: MGI:5563008
• Synonyms: Ash1l-silenced
• Gene: Ash1l Location: Chr3:88857929-88986682 bp, + strand Genetic Position: Chr3, 39.01 cM
• Alliance: Ash1l^{Tn(pb-Act-RFP)1.AF0-180T25Zhu} page

Mutation origin

• Strain of Origin: FVB/NJ

Mutation description

• Allele Type: Transposon induced (Reporter)
• Mutation: Transposon insertion
• Mutation details: The transposon containing an unspecified hybrid actin promoter driving expression of red fluorescent protein (RFP) flanked by piggyBac-specific left and right terminal sequences was co-injected with a piggyBac-containing transgene to mobilize the transposon. Line AF0-180T25 contains a transposon inserted between exon 15 and 16. (J:123680, J:208213)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ash1l Mutation: 138 strains or lines available

References

• Original: J:208213 Xia M, et al., Histone methyltransferase Ash1l suppresses interleukin-6 production and inflammatory autoimmune diseases by inducing the ubiquitin-editing enzyme A20. Immunity. 2013 Sep 19;39(3):470-81
• All: 4 reference(s)