Ikzf1^tm2.1Smale
Targeted Allele Detail

Summary

• Symbol: Ikzf1^tm2.1Smale
• Name: IKAROS family zinc finger 1; targeted mutation 2.1, Stephen T Smale
• MGI ID: MGI:5563076
• Synonyms: Ikzf1^deltaF4
• Gene: Ikzf1 Location: Chr11:11634980-11722926 bp, + strand Genetic Position: Chr11, 7.02 cM
• Alliance: Ikzf1^tm2.1Smale page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:208211
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Not Applicable)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre-mediated recombination removed exon 6, which encodes zinc finger 4, and a neomycin resistance cassette. (J:208211)

Expression

In Mice Carrying this Mutation:	3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ikzf1 Mutation: 30 strains or lines available

References

• Original: J:208211 Schjerven H, et al., Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros. Nat Immunol. 2013 Oct;14(10):1073-83
• All: 4 reference(s)