Rab27a^m1Anu
Chemically induced Allele Detail

Summary

• Symbol: Rab27a^m1Anu
• Name: RAB27A, member RAS oncogene family; mutation 1, Australian National University
• MGI ID: MGI:5563433
• Synonyms: ENU16NIH:003b coat phenotype
• Gene: Rab27a Location: Chr9:72952136-73004911 bp, + strand Genetic Position: Chr9, 40.08 cM
• Alliance: Rab27a^m1Anu page

Mutation origin

• Strain of Origin: C57BL/6JAnu
• Project Collection: APF ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to A point mutation at position 385 on cDNA (ENSMUST00000034722) in exon 3 and results in the amino acid substitution of Tryptophan to Arginine at position 72. (J:104190)
• Inheritance: Recessive

Phenotypes

Key:

hm	homozygous	ht	heterozygous	tg	involves transgenes	√	phenotype observed
cn	conditional genotype	cx	complex: > 1 genome feature	ot	other: hemizygous, indeterminate,...	N	normal phenotype

Genotype/
Background:

	Allelic Composition	Genetic Background	Cell Line(s)
Loading...
hm1	Rab27a^m1Anu/Rab27a^m1Anu	C57BL/6JAnu-Rab27a^m1Anu

Phenotypes:

Affected Systems	hm1
show or hide all annotated terms
integument	√
abnormal coat/hair pigmentation	√
pigmentation	√
abnormal coat/hair pigmentation	√

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rab27a Mutation: 147 strains or lines available

References

• Original: J:104190 The Australian Phenomics Facility at The Australian National University, Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University. MGI Direct Data Submission. 2006-2014
• All: 2 reference(s)