Etv5^sco
Chemically induced Allele Detail

Summary

• Symbol: Etv5^sco
• Name: ets variant 5; sco
• MGI ID: MGI:5563470
• Synonyms: Joey-SCO CBA
• Gene: Etv5 Location: Chr16:22200063-22258320 bp, - strand Genetic Position: Chr16, 13.3 cM, cytoband B1
• Alliance: Etv5^sco page

Etv5^sco/Etv5^sco males are sterile due to the progressive loss of germ cells

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6JAnu
• Project Collection: APF ENU Mutagenesis

Mutation description

Allele Type: Chemically induced (ENU) (Null/knockout) Mutation: Single point mutation Mutation details: ENU mutagenesis induced an A to T point mutation at coding nucleotide position 1234 (1414 on cDNA ENSMUST00000079601) in exon 12 and results in the amino acid substitution of lysine with STOP at position 412 (p.K412*). (J:104190) Inheritance: Recessive

Schematic of the location of the identified missense mutation in the Etv5^sco allele

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Etv5 Mutation: 271 strains or lines available

References

• Original: J:104190 The Australian Phenomics Facility at The Australian National University, Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University. MGI Direct Data Submission. 2006-2014
• All: 2 reference(s)