Bbip1^tm1.1Gne
Targeted Allele Detail

Summary

• Symbol: Bbip1^tm1.1Gne
• Name: BBSome interacting protein 1; targeted mutation 1.1, Genentech
• MGI ID: MGI:5563473
• Gene: Bbip1 Location: Chr19:53918292-53933058 bp, - strand Genetic Position: Chr19, 48.8 cM
• Alliance: Bbip1^tm1.1Gne page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:204140
• Parent Cell Line: C2 (Nagy) (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 2 and an FRT flanked pgk-em7-neo cassette and loxP site were inserted downstream of exon 2. Cre mediated recombination removed exon 2 and the pgk-em7-neo cassette. (J:204140)

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bbip1 Mutation: 20 strains or lines available

References

• Original: J:204140 Loktev AV, et al., Neuropeptide Y Family Receptors Traffic via the Bardet-Biedl Syndrome Pathway to Signal in Neuronal Primary Cilia. Cell Rep. 2013 Dec 12;5(5):1316-29
• All: 2 reference(s)