Pantr2^tm1Vlcg
Targeted Allele Detail

Summary

• Symbol: Pantr2^tm1Vlcg
• Name: POU domain, class 3, transcription factor 3 adjacent noncoding transcript 2; targeted mutation 1, Velocigene
• MGI ID: MGI:5563531
• Gene: Pantr2 Location: Chr1:42746221-42752614 bp, - strand Genetic Position: Chr1, Syntenic
• Alliance: Pantr2^tm1Vlcg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:204277
• Parent Cell Line: VGF1 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NTac)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Homologous recombination replaced the entire 6.5 kb gene with a lacZ reporter cassette (including Kozak sequence and ATG start codon) and a loxP site flanked neomycin resistance gene cassette. Complete ablation was confirmed by qRT-PCR. (J:204277)

Expression

In Mice Carrying this Mutation:	5 assay results 3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pantr2 Mutation: 0 strains or lines available

References

• Original: J:204277 Sauvageau M, et al., Multiple knockout mouse models reveal lincRNAs are required for life and brain development. Elife. 2013;2(0):e01749
• All: 3 reference(s)