Gt(ROSA)26Sor^{tm2(CAG-Mir128-2)Ans}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm2(CAG-Mir128-2)Ans}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Anne Schaefer
• MGI ID: MGI:5563798
• Synonyms: Rosa-miR-128
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm2(CAG-Mir128-2)Ans} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:205260
• Parent Cell Line: CY2.4 (ES Cell)
• Strain of Origin: B6(Cg)-Tyr^c-2J

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm2(CAG-Mir128-2)Ans} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Mir128-2 (MGI:3618709)

• Mutation details: A construct consisting of a CAGG promoter, floxed neo-stop cassette, Mir128-2 sequence, and an FRT flanked IRES-EGFP cassette was inserted via homologous recombination. (J:205260)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 992 strains or lines available

References

• Original: J:205260 Tan CL, et al., MicroRNA-128 governs neuronal excitability and motor behavior in mice. Science. 2013 Dec 6;342(6163):1254-8
• All: 1 reference(s)