Elavl1^tm1.1Atas
Targeted Allele Detail

Summary

• Symbol: Elavl1^tm1.1Atas
• Name: ELAV like RNA binding protein 1; targeted mutation 1.1, Ulus Atasoy
• MGI ID: MGI:5563910
• Synonyms: HuR^fl
• Gene: Elavl1 Location: Chr8:4335382-4375413 bp, - strand Genetic Position: Chr8, 2.0 cM
• Alliance: Elavl1^tm1.1Atas page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:207013
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A portion of the promoter region and exons 1 and 2 were floxed. Flp-mediated recombination removed the neomycin resistance cassette. (J:209128)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Elavl1 Mutation: 43 strains or lines available

References

• Original: J:207013 Chen J, et al., Posttranscriptional gene regulation of IL-17 by the RNA-binding protein HuR is required for initiation of experimental autoimmune encephalomyelitis. J Immunol. 2013 Dec 1;191(11):5441-50
• All: 6 reference(s)