Kmt2b^tm1Jjdh
Targeted Allele Detail

Summary

• Symbol: Kmt2b^tm1Jjdh
• Name: lysine (K)-specific methyltransferase 2B; targeted mutation 1.1, James J Hsieh
• MGI ID: MGI:5565082
• Synonyms: Mll2^nc
• Gene: Kmt2b Location: Chr7:30268283-30288151 bp, - strand Genetic Position: Chr7, 18.63 cM, cytoband A3
• Alliance: Kmt2b^tm1Jjdh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:112159
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Hypomorph)
• Mutation: Insertion
• This allele expresses a noncleavable form of the gene product.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kmt2b Mutation: 65 strains or lines available

References

• Original: J:112159 Takeda S, et al., Proteolysis of MLL family proteins is essential for Taspase1-orchestrated cell cycle progression. Genes Dev. 2006 Sep 1;20(17):2397-409
• All: 4 reference(s)