Cxcl5^tm1.1Mkch
Targeted Allele Detail

Summary

• Symbol: Cxcl5^tm1.1Mkch
• Name: C-X-C motif chemokine ligand 5; targeted mutation 1.1, Markus Koch
• MGI ID: MGI:5565192
• Synonyms: Cxcl5^{tm1.1(lacZ)MK}, Cxcl5^tm1(lacZ)MK
• Gene: Cxcl5 Location: Chr5:90907219-90909483 bp, + strand Genetic Position: Chr5, 44.78 cM
• Alliance: Cxcl5^tm1.1Mkch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:208901
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A lacZ reporter replaced the coding sequence. A self-excising neomycin resistance cassette was excised from the final allele. (J:208901)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cxcl5 Mutation: 12 strains or lines available

References

• Original: J:208901 Nouailles G, et al., CXCL5-secreting pulmonary epithelial cells drive destructive neutrophilic inflammation in tuberculosis. J Clin Invest. 2014 Mar 3;124(3):1268-82
• All: 1 reference(s)