Mrpl51^{tm1.1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Mrpl51^{tm1.1(KOMP)Vlcg}
• Name: mitochondrial ribosomal protein L51; targeted mutation 1.1, Velocigene
• MGI ID: MGI:5565611
• Gene: Mrpl51 Location: Chr6:125169163-125171355 bp, + strand Genetic Position: Chr6, 59.32 cM, cytoband F2
• Alliance: Mrpl51^{tm1.1(KOMP)Vlcg} page
• IMPC: Mrpl51 gene page

Mutation origin

• Mutant Cell Line: 11729A-A7
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 1067bp between positions 125142376-125143442 of Chromosome 6, and subsequent Cre-mediated excision deleted the neomycin selection cassette (Genome Build37). (J:136110, J:188991)

Expression

In Mice Carrying this Mutation:	55 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mrpl51 Mutation: 16 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 5 reference(s)