Mtch2^tm1Atgr
Targeted Allele Detail

Summary

• Symbol: Mtch2^tm1Atgr
• Name: mitochondrial carrier 2; targeted mutation 1, Atan Gross
• MGI ID: MGI:5566663
• Gene: Mtch2 Location: Chr2:90677499-90697154 bp, + strand Genetic Position: Chr2, 50.41 cM, cytoband E1
• Alliance: Mtch2^tm1Atgr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:209127
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons1-3 were replaced with a neomycin selection cassette. (J:209127)

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mtch2 Mutation: 26 strains or lines available

References

• Original: J:209127 Zaltsman Y, et al., MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria. Nat Cell Biol. 2010 Jun;12(6):553-62
• All: 2 reference(s)