Gsdma3^M2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Gsdma3^M2Btlr
• Name: gasdermin A3; mutation 2, Bruce Beutler
• MGI ID: MGI:5566687
• Synonyms: Mr.Magoo
• Gene: Gsdma3 Location: Chr11:98517186-98529052 bp, + strand Genetic Position: Chr11, 62.21 cM
• Alliance: Gsdma3^M2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced an A to G transition at base pair 98,635,919 on chromosome 11, or base pair 9,560 in the GenBank genomic region NC_000077. The mutation corresponds to base pair 1,113 in the NM_001007461 mRNA transcript in exon 9 of 11 total exons. The mutation results in a tyrosine (Y) to cysteine (C) substitution at amino acid 344 (Y344C). (J:209203)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gsdma3 Mutation: 26 strains or lines available

References

• Original: J:209203 Purrington T, et al., Direct Data Submission for the Mutagenetix entry for Mr.Magoo. MGI Direct Data Submission. 2014
• All: 1 reference(s)