Hsd11b1tm1.2Awhi
Targeted Allele Detail
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| Symbol: |
Hsd11b1tm1.2Awhi |
| Name: |
hydroxysteroid 11-beta dehydrogenase 1; targeted mutation 1.1, Anne White |
| MGI ID: |
MGI:5566778 |
| Gene: |
Hsd11b1 Location: Chr1:192903917-192946345 bp, - strand Genetic Position: Chr1, 97.67 cM
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| Alliance: |
Hsd11b1tm1.2Awhi page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:207713
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Conditional ready) |
| Mutation: |
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Insertion
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Mutation details: Exon 2 was flanked by loxP sites. Cre-mediated recombination removed the neomycin resistance cassette and left exon 2 floxed.
(J:207713)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Hsd11b1 Mutation: |
28 strains or lines available
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| Original: |
J:207713 Harno E, et al., 11beta-Hydroxysteroid dehydrogenase type 1 (11beta-HSD1) inhibitors still improve metabolic phenotype in male 11beta-HSD1 knockout mice suggesting off-target mechanisms. Endocrinology. 2013 Dec;154(12):4580-93 |
| All: |
1 reference(s) |
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Analysis Tools
