Zic2em4Bend
Endonuclease-mediated Allele Detail
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Symbol: |
Zic2em4Bend |
Name: |
zinc finger protein of the cerebellum 2; endonuclease-mediated mutation 4, Ben Davies |
MGI ID: |
MGI:5566855 |
Synonyms: |
C3H-10, Zic2A10 |
Gene: |
Zic2 Location: Chr14:122712847-122717264 bp, + strand Genetic Position: Chr14, 65.97 cM
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Alliance: |
Zic2em4Bend page
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Curly tail in a Zic2em4Bend/Zic2+ founder
Show the 1 phenotype image(s) involving this allele.
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Allele Type: |
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Endonuclease-mediated (Null/knockout) |
Mutation: |
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Intragenic deletion
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Mutation details: TALEN mediated recombination introduced a 2 bp deletion resulting in a Lysine to Asparagine mutation at amino acid 399 and a frameshift mutation (p.Lys399Asnfs*17).
(J:199882)
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TALEN mediated recombination scheme used to generate the Zic2em1Bend, Zic2em2Bend, Zic2em3Bend, Zic2em4Bend and Zic2em5Bend alleles |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Zic2 Mutation: |
41 strains or lines available
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Original: |
J:199882 Davies B, et al., Site specific mutation of the Zic2 locus by microinjection of TALEN mRNA in mouse CD1, C3H and C57BL/6J oocytes. PLoS One. 2013;8(3):e60216 |
All: |
2 reference(s) |
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