Slc39a5^tm1Gka
Targeted Allele Detail

Summary

• Symbol: Slc39a5^tm1Gka
• Name: solute carrier family 39 (metal ion transporter), member 5; targeted mutation 1, Glen K Andrews
• MGI ID: MGI:5566985
• Synonyms: Zip5^Fx
• Gene: Slc39a5 Location: Chr10:128231800-128237098 bp, - strand Genetic Position: Chr10, 76.55 cM, cytoband D3
• Alliance: Slc39a5^tm1Gka page

Slc39a5^tm1Gka/Slc39a5^tm1Gka Tg(Cela1-cre/ERT)1Lgdn/0 mice exhibit increased sensitivity to zinc-induced acute pancreatitis

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: A loxP site was inserted into a poorly conserved region in intron 4 and a second loxP site and neomycin selection cassette were inserted downstream from exon 12. (J:94077)

Generation of the Slc39a5^tm1Gka and Slc39a5^tm1.1Gka alleles

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Slc39a5 Mutation: 28 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 2 reference(s)