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Fbxw11tm1Ybn
Targeted Allele Detail
Summary
Symbol: Fbxw11tm1Ybn
Name: F-box and WD-40 domain protein 11; targeted mutation 1, Yinon Ben-Neriah
MGI ID: MGI:5568086
Synonyms: beta-TrCP2f
Gene: Fbxw11  Location: Chr11:32592724-32696816 bp, + strand  Genetic Position: Chr11, 19.02 cM
Alliance: Fbxw11tm1Ybn page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:206654
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsThe targeting vector was designed to insert a loxP-flanked neomycin cassette and a third loxP site was used to flank exon 4. (J:206654)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fbxw11 Mutation:  72 strains or lines available
References
Original:  J:206654 Kanarek N, et al., Critical role for IL-1beta in DNA damage-induced mucositis. Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):E702-11
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory