Mir192^tm1.1Rnat
Targeted Allele Detail

Summary

• Symbol: Mir192^tm1.1Rnat
• Name: microRNA 192; targeted mutation 1.1, Rama Natarajan
• MGI ID: MGI:5568207
• Gene: Mir192 Location: Chr19:6314874-6314962 bp, + strand Genetic Position: Chr19, 4.39 cM
• Alliance: Mir192^tm1.1Rnat page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:208963
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The sequence was replaced with a floxed neomycin resistance cassette. Cre-mediated recombination removed the selection cassette. (J:208963)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir192 Mutation: 2 strains or lines available

References

• Original: J:208963 Deshpande SD, et al., Transforming growth factor-beta-induced cross talk between p53 and a microRNA in the pathogenesis of diabetic nephropathy. Diabetes. 2013 Sep;62(9):3151-62
• All: 2 reference(s)