Il9^tm1Flv
Targeted Allele Detail

Summary

• Symbol: Il9^tm1Flv
• Name: interleukin 9; targeted mutation 1, Richard A Flavell
• MGI ID: MGI:5568753
• Gene: Il9 Location: Chr13:56627090-56630059 bp, - strand Genetic Position: Chr13, 30.06 cM
• Alliance: Il9^tm1Flv page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:208730
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: BALB/c

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced exons 1 through 4. RT-PCR confirmed the absence of transcript expression in mice subcutaneously infected with N. brasiliensis larvae. (J:208730)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il9 Mutation: 22 strains or lines available

References

• Original: J:208730 Licona-Limon P, et al., Th9 Cells Drive Host Immunity against Gastrointestinal Worm Infection. Immunity. 2013 Oct 17;39(4):744-57
• All: 2 reference(s)